Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial

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A trial that overwhelmingly showed the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment (IMPACT) collaborative care management program for late-life depression. At 12 months, 45% of intervention patients had a 50% or greater reduction in depressive symptoms from baseline compared with 19% of usual care participants. Intervention patients also experienced greater rates of depression treatment, more satisfaction with depression care, lower depression severity, less functional impairment, and greater quality of life than participants assigned to the usual care group.

Journal of the American Medical Association (JAMA)
Publication date
December 11, 2002
Unutzer, et al.